Nowadays, obesity is a major problem in many countries – Greece included. Anxiety and stress often lead to overeating. During stress, the body produces higher levels of cortisol (stress hormone), which can cause weight gain. Increased cortisol levels trigger a number of unwanted conditions such as sleep problems, blood sugar imbalances and increased appetite. According to research, cannabidiol has an anxiolytic effect that helps regulate cortisol levels and, by extension, reduce appetite that leads to weight gain. Appetite is stimulated by two main hormones: Ghrelin and Leptin. The part of our brain that regulates Ghrelin is stimulated by CB1 receptors. Studies have shown that CBD blocks CB1 receptors, meaning that the hunger hormone can be reduced so that it functions at normal levels.
Cardiovascular disease is a general term for conditions affecting the heart or blood vessels. Cannabis is effective in patients with cardiovascular diseases, such as coronary artery disease (angina), cerebrovascular disease, and end-stage heart failure, as it has the ability to lower blood pressure by dilating arteries and reducing the damage caused by heart attacks and strokes. . In particular, it causes vasodilation, which is a known effect of cannabinoids. Exo- and Endo-cannabinoids have a protective role on cardiac function in the treatment of ischemia, shock and myocardial infarction.
The endocannabinoid system with the action of CB2 receptors is an important protective mechanism against myocardial ischemia. In fact, the extent of the heart attack is reduced by 66% with the administration of CBD which significantly reduces myocardial inflammation. Cannabidiol is cardioprotective against ischemia and a very promising treatment, without side effects.